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Clinical Development

Supporting recruitment for a rare oncology study in Germany

A sponsor running a rare oncology study in Germany partnered with admedicum to improve study recruitment (anonymized case study).

Situation

A biotechnology company running an early-phase clinical study in rare oncology in Germany faced challenging recruitment, driven by highly restrictive eligibility criteria within an already limited patient subpopulation.

Objective

Build a compliant, patient-friendly recruitment pathway for a rare oncology study recruiting in Germany, enabling early identification of potentially eligible patients, structured pre-screening, and efficient referral to investigational sites.

Our Solution

1
Created a compliant patient-facing website for the study (German language, clear study scope, privacy and consent flows) to capture interest in a structured way.
2
Executed multi-channel outreach via patient organizations (POs), HCP networks, and targeted online advertising, supported by short educational videos, teasers and radio broadcasts to raise awareness and explain the study and next steps in a compliant way.
3
Implemented web-based pre-screening tailored to the strict eligibility criteria, helping to identify potentially eligible patients and reducing recruitment burden of clinical trial sites.
4
Set up a referral and follow-up workflow to guide potentially eligible patients toward the appropriate investigational sites in Germany, including documentation and KPI reporting for recruitment steering.

Outcomes and Impact

1
Increased the volume of patient inquiries through different recruitment channels, creating a reliable top-of-funnel for a rare oncology population in Germany.
2
Improved recruitment efficiency by pre-screening against restrictive eligibility criteria, reducing avoidable site workload.
3
Successful completion of enrollment in an extremely rare terminal cancer indication.

We embraced admedicum’s services only by the time that we became aware that the inclusion of patients was not as expected due to the very restrictive nature of the eligibility criteria. The admedicum team’s experience and creativity
towards a fruitful approach to our reality of clinical study conduct within Germany clearly translated in a gateway towards potentially eligible patients, whom, upon a triage, could ultimately be guided in contacting the investigational sites.

Chief Medical Officer

Conclusion

admedicum addresses recruitment challenges in complex indications through compliant patient outreach, digital pre-screening, and structured site referral. This approach accelerates patient identification, enhances recruitment efficiency, and reduces workload for investigational sites.

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