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Patient Engagement & Advocacy
Pre-Clinical Development

Clinical Research & Development Through Patient Partnership

The impact of patient-relevant engagement to raise awareness and drive recruitment in a phase II clinical trial.

Situation

In the SUISSE MPC-2 study, a phase II clinical trial exploring a novel cell-based therapy for women with stress urinary incontinence, the teams from University of Zurich and MUVON Therapeutics, faced a unique set of challenges. The condition itself is often surrounded by stigma, making open discussion difficult for many women. In addition, the study’s design included strict eligibility criteria and was conducted at a single site, which further limited access for potential participants. Given the novelty of the investigated treatment, clear, honest, and empathetic communication was essential to build trust and encourage participation.

Objective

The objective was to break through barriers of awareness and trust and reach potential eligible patients who might benefit from this therapy. Recognizing that patients are not just study subjects but true partners in research, admedicum stepped in with its recruitment approach, a modular framework designed to support patients at every stage of their journey. This approach was built to ensure that individuals felt informed, understood, and empowered.

Our Solution

1
Patient-friendly website with a digital pre-screener: A dedicated, easy‑to‑navigate website served as a welcoming first point of contact. Co‑created with patient input and the study physician, it included a digital pre‑screener that allowed potential participants to check their eligibility conveniently from home, reducing barriers to initial engagement.
2
Video interview with the Principle Investigator: To further build trust, a video interview featuring the study’s lead physician was shared. This gave potential participants the chance to hear directly from the expert behind the research, helping to personalize the study, and demystify the process.
3
Targeted outreach via social media, patient communities, and healthcare professionals: Awareness was raised through targeted outreach, leveraging the power of social media and patient advocacy groups. Healthcare professionals also played a crucial role, informing potentially eligible women and addressing questions and concerns.
4
Study information service: A dedicated, personalized, empathetic phone and email service for potential participants. Trained female staff provided a safe and confidential space to ask questions about the study, the condition, or the investigational treatment, helping to address stigma, uncertainty, and personal discomfort.

Outcomes and Impact

1
Transparent, compassionate communication and a patient-centred approach strengthened trust and credibility within the patient community.
2
Personalized support helped potential participants better understand the study and feel informed throughout the recruitment journey, supporting a more positive participant experience.
3
Targeted outreach and validated patient-centric communication strategies contributed to efficient recruitment in a real-world clinical trial setting.
4
Pre-qualified patient referrals and direct participant support reduced the recruitment burden for site investigators.

“What we do not research, remains hidden: Incontinence in women deserves visibility and scientific attention.”

Quote from participating patient

"We are delighted to have engaged with admedicum early in the process of preparing our clinical trial ... . The admedicum team’s strategic and operational know-how as well as their legal and regulatory expertise provided a seamless service not only for patients but also for us as a Sponsor resulting in a streamlined and efficient recruitment process."

Deana Mohr
Project Leader MUVON

Conclusion

admedicum contributed to a seamless and efficient recruitment process by combining patient engagement expertise with strategic, operational, and regulatory know-how. Through these combined efforts, the clinical study turned recruitment into an efficient and collaborative process. By addressing the voices and concerns of women with stress urinary incontinence, patient-focused engagement broke down barriers, built trust, and encouraged participation.

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